Macleods on June 26 also recalled 32 lots of losartan potassium including two lots of 50 mg tablets and losartan potassium/hydrochlorothiazide tablets, including 12 lots of 50 mg/12.5 mg strength, three lots of 100 mg/12.5 mg and 15 lots of 100 mg/25 mg strength. If you are taking any medication containing valsartan, losartan or irbesartan, compare the information on your prescription bottle with the information in this list (company, National Drug Code, lot number) to determine if your current medicine has been recalled. The recalled drugs are part a large class called angiotensin II receptor blockers (ARBs). Camber Pharmaceuticals on Feb. 28 recalled 87 lots of losartan tablets USP 25mg, 50 mg and 100 mg. See the affected products and what the label looks like. A link has been sent to your friend's email address. If you buy a can of tomatoes or infant formula, you will find a Lot Number and a Use By/Expiration Date. The Public Interest Research Group said in March that the FDA needs to step up the pace. (I was also on Cozaar and then Avapro). You can check the status by entering your device serial number printed on … For valsartan-containing products currently recalled. The impurity found in these batches is N-Methylnitrosobutyric acid (NMBA). See the full list here. A common thread among all of these recalls is that the drugs, or ingredients in the drugs, were all made in China or India. Note: This story was updated on Sept. 23, 2019, with an additional losartan recall from Torrent Pharmaceuticals. An FDA spokesman says the agency is still investigating how these drugs became contaminated. Supermarkets scan products during check out. I never had a problem until this new doctor switched me to generics in October of … Losartan is now the third “sartan” drug that has been recalled after the carcinogen N-Nitrosodiethylamine (NDEA) was detected in its active pharmaceutical ingredient. Numerous blood pressure medications in recent months have been recalled over concerns of possibly carcinogenic ingredients. At its peak level, losartan inhibits 85% of the effects of angiotensin II, and 25 to 40% or this inhibition persists for 24 hours. What blood pressure drugs have been recalled? But at least one expert says the recalls are making it more difficult to find valsartan drugs that have not been recalled. If you experience negative side effects while taking this drug, a number of other medications are available that work differently than Losartan. It may take up to a week for significant blood pressure lowering or kidney effects are noted, with maximal effects occurring in 3 to 6 weeks. These drugs work by widening or relaxing blood vessels, thus lowering blood pressure. Losartan Potassium was distributed by pharmacies nationwide. A widespread recall of common blood pressure and heart failure medications has been expanded to include more drugs containing losartan due to … FDA.gov: "Statement from FDA Commissioner Scott Gottlieb, M.D., and Janet Woodcock, M.D., director of the Center for Drug Evaluation and Research on the agency’s list of known nitrosamine-free valsartan and ARB class medicines, as part of agency’s ongoing efforts to resolve ongoing safety issue;" "Legacy Pharmaceutical Packaging, LLC Issues Voluntary Nationwide Recall of Losartan Potassium Tablets, USP, 50mg Due to the Detection of Trace Amounts of N-Nitroso N-Methyl 4-amino butyric acid (NMBA) Impurity found in the Active Pharmaceutical Ingredient (API)," "Legacy Pharmaceutical Packaging, LLC Issues Voluntary Nationwide Recall of Losartan Potassium Tablets, USP, 25mg, 50mg, And 100mg Due to The Detection of Trace Amounts Of N-Nitroso N-Methyl 4-Amino Butyric Acid (NMBA) Impurity Found in The Active Pharmaceutical Ingredient (API)," "FDA approves a new generic valsartan," “UPDATED:ADDITIONAL LOTS ADDED: Torrent Pharmaceuticals Limited Issues Voluntary Nationwide Recall of Valsartan/Amlodipine/HCTZ, Valsartan/Amlodipine and Valsartan Tablets,” “FDA provides update on its ongoing investigation into valsartan products; and reports on the finding of an additional impurity identified in one firm’s already recalled products,” “Analysis of N-nitrosodimethylamine (NDMA) Levels in Recalled Valsartan in the U.S.,” “FDA updates on angiotensin II receptor blocker (ARB) recalls including valsartan, losartan and irbesartan,” “Irbesartan products under recall - Updated October 29, 2018,” “Sciegen Pharmaceuticals, Inc. Issues Voluntary Nationwide Recall of Irbesartan Tablets, USP 75 Mg, 150 Mg, and 300 Mg Due to The Detection of Trace Amounts of NDEA (N-Nitrosodiethylamine) Impurity Found in The Active Pharmaceutical Ingredient (API),” “Sandoz Inc. Issues Voluntary Nationwide Recall of One Lot of Losartan Potassium and Hydrochlorothiazide Due to the Detection of Trace Amounts of NDEA (N-Nitrosodiethylamine) Impurity Found in the Active Pharmaceutical Ingredient (API),” “Valsartan products not currently recalled - Updated December 4, 2018,” “Valsartan products under recall - Updated December 4, 2018.”. The impurity, known as NDEA, was found in the drug’s key ingredient made by Zhejiang Huahai Pharmaceutical Co. in China. See which products were affected by the recall. For more information on the recalls, read all of USA TODAY's coverage here: Jan. 23: Blood pressure medication recall over cancer risk expanded for more losartan drugs, Jan. 18: FDA: Another blood pressure drug, irbesartan, recalled over cancer-causing impurity, Jan. 14: Blood pressure drug recall: FDA investigates foreign plants that made drugs with cancer-causing impurities, Jan. 7: More blood pressure medication recalled over carcinogen concerns — this time, losartan, Jan. 2: More blood pressure medication recalled: Company recalls 80 lots of valsartan over cancer concerns, Dec. 6: Three more blood pressure drugs recalled over cancer concern: Here's what you need to know, Nov. 30: Doctors: Blood pressure drug substitutes are available for patients affected by recalls, Nov. 30: Two more blood pressure drugs recalled for potential cancer risk, Nov. 14: FDA chief: Blood pressure medicine recalls reflect increased scrutiny on drug safety, Nov. 13: FDA recalls another blood pressure drug for possible cancer risk, Nov. 2: Blood pressure drug recalled for possible cancer risk, FDA says, Aug. 7: FDA expands recall of heart drug for possible cancer-causing contamination, Contributing: Ken Alltucker, USA TODAY. The drugs were made in India and distributed by Heritage Pharmaceuticals of East Brunswick, NJ. Not all ARBs contain NDMA or NDEA or are under recall, the FDA says. The FDA is also working to determine what exactly has caused the impurities and what changes need to be made in the manufacturing process to prevent it. Here’s what to watch out for. Once there, you can check a list of current medication recalls. To find out whether your medication is under recall, check the FDA website for all three drugs. The latest recall was this expansion to 40 repacked lots. Dozens of medications used to treat high blood pressure have been recalled over the past several months as federal investigators discover potentially cancer-causing impurities in them. In previous reports the FDA has indicated that the level of risk to individual patients is very low, but it’s still high enough to warrant the recall. The first thing you should do is contact your physician or … The amount of NDMA found in the recalled valsartan drugs exceeds acceptable levels. See a list of affected products here and here. Follow USA TODAY's Ryan Miller on Twitter: @RyanW_Miller. NDMA and NDEA are probable carcinogens, and the FDA has found levels of the impurities in three drugs: valsartan, irbesartan and losartan-containing products, the agency says. To find out whether your specific product has been recalled, look for the drug name, manufacturer name, and lot number on the label of your prescription bottle. You can find the list here. Not all valsartan-, losartan-, or irbesartan-containing medications are affected and being recalled. Date 06/2020. How Do I Know if my Valsartan Has Been Recalled? Ryan W. Miller. Craig Beavers, PharmD, cardiovascular clinical pharmacy coordinator, University of Kentucky Medical Center. NDEA is found naturally in certain … Losartan potassium hydrochlorothiazide (Losartan) was also recalled by Sandoz Inc. in November over cancer concerns due to an impurity impurity N-nitrosodiethylamine, according to … Yet another blood pressure drug has been recalled because of fears of impurities added by a lab in China. This product is being recalled due to the trace amount of an impurity, N-nitrosodiethylamine (NDEA) contained in the API Losartan, USP manufactured by … These are not yet listed on the FDA's website of all recalled ibersartan products. What is the risk of getting cancer from one of these drugs? Sen. Chuck Grassley of Iowa tweets he has tested positive for COVID-19. NDEA is used to make rocket fuel and can also be found in some food and drinking water, but at low levels. I have some of the recalled Losartan; what do I do now? Company: Medicine: National Drug Code (NDC) Lot Number: Expiration: A-S Medication … The product can be identified by checking the product name and repackaged lot number on the bottle containing these products. USA TODAY. What do I do if I think I have recalled losartan? Numerous blood pressure medications in recent months have been recalled over concerns of possibly carcinogenic ingredients. The FDA estimates that if 8,000 people took the highest valsartan dose, which is 320 milligrams, from recalled batches every day for 4 years, there would likely only be one additional case of cancer over the life of those 8,000 people.